| Uruguay Reserve League | 2024/12/02 20:00 | Defensor Sporting Reserves v Nacional de Montevideo Reserves | D | 0-0 |
| Uruguay Reserve League | 2024/06/17 18:00 | Nacional de Montevideo Reserves v Defensor Sporting Reserves | W | 2-1 |
| Uruguay Reserve League | 2023/11/27 19:00 | Nacional de Montevideo Reserves v Defensor Sporting Reserves | D | 1-1 |
| Uruguay Reserve League | 2023/05/08 13:00 | Defensor Sporting Reserves v Nacional de Montevideo Reserves | W | 1-2 |
| Uruguay Reserve League | 2022/11/21 19:00 | Nacional de Montevideo Reserves v Defensor Sporting Reserves | W | 3-1 |
| Uruguay Reserve League | 2022/05/24 17:00 | Defensor Sporting Reserves v Nacional de Montevideo Reserves | W | 1-3 |
| Uruguay Reserve League | 2020/10/27 18:00 | Defensor Sporting Reserves v Nacional de Montevideo Reserves | W | 0-1 |
| Uruguay Reserve League | 2019/08/27 18:00 | Defensor Sporting Reserves v Nacional de Montevideo Reserves | L | 3-2 |
| Uruguay Reserve League | 2025/04/14 15:00 | Torque Reserves v Nacional de Montevideo Reserves | W | 2-3 |
| Uruguay Reserve League | 2025/04/08 19:00 | Nacional de Montevideo Reserves v Montevideo Wanderers Reserves | D | 1-1 |
| Uruguay Reserve League | 2025/03/31 19:00 | Boston River Reserves v Nacional de Montevideo Reserves | W | 1-2 |
| Uruguay Reserve League | 2025/03/24 19:00 | Nacional de Montevideo Reserves v Club Oriental Reserves | W | 3-0 |
| Uruguay Reserve League | 2025/03/13 19:30 | Atletico River Plate Reserves v Nacional de Montevideo Reserves | D | 1-1 |
| Uruguay Reserve League | 2025/03/10 19:30 | Nacional de Montevideo Reserves v Liverpool Montevideo Reserves | L | 0-1 |
| Uruguay Reserve League | 2025/02/24 22:00 | Nacional de Montevideo Reserves v Club Atletico Progreso Reserves | L | 1-3 |
| Uruguay Reserve League | 2024/12/09 13:00 | Atletico Fenix Reserves v Nacional de Montevideo Reserves | W | 2-3 |
| Uruguay Reserve League | 2025/04/17 18:00 | Montevideo Wanderers Reserves v Defensor Sporting Reserves | W | 0-2 |
| Uruguay Reserve League | 2025/04/14 16:30 | Defensor Sporting Reserves v Club Oriental Reserves | W | 3-1 |
| Uruguay Reserve League | 2025/04/08 12:30 | Liverpool Montevideo Reserves v Defensor Sporting Reserves | D | 0-0 |
| Uruguay Reserve League | 2025/03/31 12:00 | Defensor Sporting Reserves v Club Atletico Progreso Reserves | D | 3-3 |
| Uruguay Reserve League | 2025/03/24 19:00 | Racing Club de Montevideo Reserves v Defensor Sporting Reserves | D | 1-1 |
| Uruguay Reserve League | 2025/03/17 12:30 | Defensor Sporting Reserves v Juventud De Las Piedras Reserves | L | 1-2 |
| Uruguay Reserve League | 2025/03/10 19:30 | Penarol Reserves v Defensor Sporting Reserves | W | 0-1 |
| Uruguay Reserve League | 2025/02/28 12:00 | Defensor Sporting Reserves v Torque Reserves | L | 2-3 |