Stadium: Dedmon Center
Home Manager: Darris Nichols Away Manager: Dave Dickerson
| NCAAB | 2022/01/06 21:00 | Radford v USC Upstate | L | 82-77 |
| NCAAB | 2021/02/05 23:00 | USC Upstate v Radford | L | 66-102 |
| NCAAB | 2021/02/04 23:00 | USC Upstate v Radford | L | 61-63 |
| NCAAB | 2020/02/22 21:30 | USC Upstate v Radford | L | 60-81 |
| NCAAB | 2020/01/16 23:00 | Radford v USC Upstate | L | 63-59 |
| NCAAB | 2019/01/11 00:00 | Radford v USC Upstate | L | 79-72 |
| NCAAB | 2022/11/16 00:00 | USC Upstate v Clemson | L | 70-81 |
| NCAAB | 2022/11/11 23:30 | USC Upstate v Duke | L | 38-84 |
| NCAAB | 2022/11/08 00:30 | Brevard v USC Upstate | W | 42-90 |
| NCAAB | 2022/03/22 00:00 | USC Upstate v South Alabama | L | 79-83 |
| NCAAB | 2022/03/15 22:30 | USC Upstate v Appalachian State | W | 80-74 |
| NCAAB | 2022/03/05 17:00 | USC Upstate v Longwood | L | 70-79 |
| NCAAB | 2022/03/04 19:30 | Charleston Southern v USC Upstate | W | 62-72 |
| NCAAB | 2022/02/26 21:00 | Gardner Webb v USC Upstate | W | 70-72 |
| NCAAB | 2022/11/15 00:00 | Radford v Bridgewater Eagles | W | 97-46 |
| NCAAB | 2022/11/11 01:00 | Radford v Notre Dame | L | 76-79 |
| NCAAB | 2022/11/08 01:30 | Radford v Marquette | L | 69-79 |
| NCAAB | 2022/03/02 16:30 | North Carolina A&T v Radford | L | 78-71 |
| NCAAB | 2022/02/26 22:00 | Radford v North Carolina A&T | W | 62-53 |
| NCAAB | 2022/02/24 00:00 | Radford v Longwood | L | 66-71 |
| NCAAB | 2022/02/19 19:00 | High Point v Radford | W | 64-66 |
| NCAAB | 2022/02/16 23:30 | Campbell v Radford | W | 67-71 |